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Research Article Free access | 10.1172/JCI106597
Streptococcal Disease Unit, General Hospital, San Fernando, Trinidad-Tobago
Department of Medicine, Northwestern University-McGaw Medical Center, Chicago, Illinois 60611
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Streptococcal Disease Unit, General Hospital, San Fernando, Trinidad-Tobago
Department of Medicine, Northwestern University-McGaw Medical Center, Chicago, Illinois 60611
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Streptococcal Disease Unit, General Hospital, San Fernando, Trinidad-Tobago
Department of Medicine, Northwestern University-McGaw Medical Center, Chicago, Illinois 60611
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Streptococcal Disease Unit, General Hospital, San Fernando, Trinidad-Tobago
Department of Medicine, Northwestern University-McGaw Medical Center, Chicago, Illinois 60611
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Streptococcal Disease Unit, General Hospital, San Fernando, Trinidad-Tobago
Department of Medicine, Northwestern University-McGaw Medical Center, Chicago, Illinois 60611
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Streptococcal Disease Unit, General Hospital, San Fernando, Trinidad-Tobago
Department of Medicine, Northwestern University-McGaw Medical Center, Chicago, Illinois 60611
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Streptococcal Disease Unit, General Hospital, San Fernando, Trinidad-Tobago
Department of Medicine, Northwestern University-McGaw Medical Center, Chicago, Illinois 60611
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Streptococcal Disease Unit, General Hospital, San Fernando, Trinidad-Tobago
Department of Medicine, Northwestern University-McGaw Medical Center, Chicago, Illinois 60611
Find articles by Earle, D. in: JCI | PubMed | Google Scholar
Published June 1, 1971 - More info
The relation of seven different M types of streptococci to acute glomerulonephritis associated with skin lesions in South Trinidad has been studied by means of type-specific antibody assays as well as by isolation and identification of the strains. The data indicate that, one after another, five of these strains have prevailed among patients with acute glomerulonephritis during the past five years. At least three of the strains (M-types 55, 49, 57, and/or 60) were associated with epidemic increases in nephritis cases. The appearance of five consecutively predominant types of nephritogenic streptococci during a relatively short period of time is in contrast to the continuing prevalence of M-type 12 strains among nephritogenic streptococci primarily associated with respiratory infections in temperate zones. These observations suggest that the skin sores commonly found on children in tropical Trinidad, provide a particularly suitable environment for development of nephritogenic types. It remains to be seen whether these types will recur or whether new types will continue to emerge in Trinidad.
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