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Video abstracts

In this video collection, authors of findings published in JCI Insight present personally guided tours of their results. The journal accepts video submissions from authors of recently accepted manuscripts. Instructions can be found on the Video Abstracts Guidelines page.

Regulating bile duct epithelial injury in erythroid cells

In this episode, Li Yang and colleagues discuss how hepatic CD71+ erythroid cells play an immunoregulatory role in biliary atresia by suppressing the activation of hepatic lymphocytes.


Diabetes-associated genetic variation alters insulin secretion

In this Episode, Adrian Vella and colleagues discuss abnormal insulin pulse characteristics in non-diabetic individuals are linked with diabetes-associated variation in TCF7L2 and may serve as early markers of β cell dysfunction.


Drug delivery platform targets lower airway inflammation

In this episode, Krishnendu Roy, Rabindra Tirouvanziam, Amit Gaggar, and colleagues describe the development of a drug delivery platform that allows direct targeting of lung neutrophils under inflammatory conditions.

 


Composite signature for prediction of T1D progression

In this episode, Cate Speake and colleagues employ an analytical method that incorporates reproducibility testing to identify a composite signature prognostic for type 1 diabetes disease progression after diagnosis.


Itch in the gut

In this episode, Stuart Brierley and colleagues link itch in the gut to nerve sensitization and chronic intestinal pain and provide an animation illustrating the potential clinical implications of this work.

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