What determines glomerular capillary permeability?
J. Clin. Invest. William M. Deen, et al. 114:1412 doi:10.1172/JCI23577 [
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Figure 1Glomerular capillary wall, consisting principally of a fenestrated endothelium, a basement membrane, and epithelial foot processes. The foot processes form filtration slits spanned by slit diaphragms. Also shown is the endothelial cell coat, or glycocalyx. Some approximate dimensions are (
8,
10): minimum diameter of fenestra, 30 nm; GBM thickness, 200–400 nm (depending on species); width of filtration slit, 40 nm. The glycocalyx thickness is uncertain. Figure is not drawn to scale.
