Rapidly cycling fetal and neonatal hematopoietic stem cells (HSCs) generate a pool of quiescent adult HSCs after establishing hematopoiesis in the bone marrow. We report an essential role for the trithorax group gene absent, small, or homeotic 1-like (
Morgan Jones, Jennifer Chase, Michelle Brinkmeier, Jing Xu, Daniel N. Weinberg, Julien Schira, Ann Friedman, Sami Malek, Jolanta Grembecka, Tomasz Cierpicki, Yali Dou, Sally A. Camper, Ivan Maillard
In vivo proliferation history shows decreased quiescence of