Impaired regulation of NF-κB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice
J. Clin. Invest. Jun Zhang, et al. 116:3042 doi:10.1172/JCI28746 [Go to this article.]

Figure 1
T and B cell development in Cyld^–/– mice. (A) Thymocytes from 4- to 6-week-old mice were analyzed for CD4 and CD8 expression. In each panel 10,000 cells were analyzed. Numbers indicate the percentage of cells in each subset. Data are representative of 4 experiments with 5 mice of each genotype. (B) Spleen populations as determined by flow cytometry from 6- to 8-week-old mice. Data are mean ± SD calculated from 5 mice of each genotype.