Negative regulation by thyroid hormone receptor requires an intact
coactivator-binding surface
J. Clin. Invest. Tania M. Ortiga-Carvalho, et al. 115:2517 doi:10.1172/JCI24109 [
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Figure 6Gsta (
A) and
Doi1 (
B) mRNA levels in the liver of the
TR- β
WT/WT,
TR- β
E457A/WT, and
TR- β
E457A/E457A mice according to quantitative RT-PCR analysis. Data were normalized for each mRNA level relative to the values for the WT animals. Five to 10 animals were evaluated in each group, and data are shown as mean ± SEM.