Differential impact of prostaglandin H synthase 1 knockdown on platelets and parturition
J. Clin. Invest. Ying Yu, et al. 115:986 doi:10.1172/JCI23683 [
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Figure 7Serum sex hormones and uterine OTR expression in PGHS1
Neo/Neo, PGHS1-KO, and WT mice at late gestation. (
A and
B) Serum progesterone and estradiol concentrations during late gestation, respectively. Blood was collected via the saphenous vein from mice of each genotype group (n = 4–10) and concentration was determined by sequential competitive immunoassay. *P < 0.001 versus PGHS1
Neo/Neo and WT mice at day 19. (
C) mRNA expression of OTR in uterus at gestation day 19. Semiquantitative RT-PCR was performed with primers spanning one 11-kb intron to avoid genomic DNA contamination. (
D) Relative level of OTR to β-actin expression.
