Differential impact of prostaglandin H synthase 1 knockdown on platelets and parturition
J. Clin. Invest. Ying Yu, et al. 115:986 doi:10.1172/JCI23683 [Go to this article.]

Figure 6
PGHS1 expression and PG profiles in uterus during late-stage pregnancy. (A) Immunohistochemical analysis of PGHS1 in uterus at gestation day 18.5 (magnification, ×200). Red arrows represent PGHS1 staining within decidua (endometrium). (B) PGHS1 gene expression in uterus at gestation day 17.5 by real-time RT-PCR detection. (C) PG profiles in PGHS1^Neo/Neo, PGHS1-KO, and WT mice at gestation day 19. PGs were extracted from uteri isolated from each group and measured by LC/MS/MS. PGF_2α, PGE₂, and PGD₂ levels in PGHS1^Neo/Neo mice (n = 6) were 8%, 3.3%, and 3.2%, respectively, of those in WT mice (n = 10).