Stat-3 is required for pulmonary homeostasis during hyperoxia
J. Clin. Invest. Isamu Hokuto, et al. 113:28 doi:10.1172/JCI19491 [
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Figure 11Increased IL-1β, IL-6, and MIP-2 in
Stat-3Δ/Δ mice after 95% O
2. IL-1β, IL-6, and MIP-2 were measured in lung tissue from control and
Stat-3Δ/Δ mice exposed to room air or 95% O
2 for 65 hours. Levels of each cytokine were significantly increased in the
Stat-3Δ/Δ mice after hyperoxia,
n = 5 per group, as determined by ANOVA; *
P < 0.001 versus others.
