Importance of minor histocompatibility antigen expression by nonhematopoietic tissues in a CD4⁺ T cell–mediated graft-versus-host disease model
J. Clin. Invest. Stephen C. Jones, et al. 112:1880 doi:10.1172/JCI19427 [Go to this article.]

Figure 1
Minor histocompatibility antigen expression by host hematopoietic tissues alone does not elicit lethal GVHD. Established [BALB.B→BALB.B], [BALB.B→B6], and [B6→B6] BM chimeras were reirradiated (10 Gy, split dose) and injected with 2 × 10⁶ B6 ATBM cells in combination with 1.5 × 10⁷ B6 CD4⁺ T cells. (a) Survival of transplanted recipients. (b) Body weights for each group normalized as the mean percentage initial body weight ± SEM over sequential 1-week periods. n = 5 for B6→[BALB.B→BALB.B] and [BALB.B→B6], and n = 6 for B6→[B6→B6].