Coordinated tumor immunity
J. Clin. Invest. Glenn Dranoff, et al. 111:1116 doi:10.1172/JCI18359 [
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Figure 1Coordinated tumor immunity. Forni and colleagues (
9) show that immune-mediated rejection of established Her-2 positive breast tumors requires CD4
+ and CD8
+ T cells, CD1d-restricted NK T cells, neutrophils, macrophages, antibodies (Ab’s), Fc receptors, IFN-γ, and perforin.