A role for CD44 in an antigen-induced murine model of pulmonary eosinophilia
J. Clin. Invest. Shigeki Katoh, et al. 111:1563 doi:10.1172/JCI16583 [
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Figure 6Expression and HA-binding ability of CD44 on spleen cells and alveolar macrophages in Asc-exposed mice treated with anti-CD44 mAb’s. Expression and HA-binding ability of CD44 on spleen cells (
a) and alveolar macrophages (
b) were assessed in mice 24 h after allergen challenge as described in Methods. Data represent mean ± SEM of percentages of positive cells compared with negative control in flow-cytometric analysis. The values shown are averaged from three to five independent experiments. *Significant differences (
P < 0.05) between Asc-challenged anti-CD44 mAb-treatment mice (Asc/KM201 or Asc/IM7) and Asc-challenged RIgG-treatment mice (Asc/RIgG).