Impaired Smad7-Smurf–mediated negative regulation of TGF-β signaling in scleroderma fibroblasts
J. Clin. Invest. Yoshihide Asano, et al. 113:253 doi:10.1172/JCI16269 [Go to this article.]

Figure 5
Expression levels of Smad7 in normal and scleroderma dermal tissue. Paraffin sections of normal dermal tissue (a) and scleroderma dermal tissue (b) were subjected to immunohistochemical analysis with anti-Smad7 Ab, as described in Methods. The immunoreactivity for Smad7 is indicated by arrows.