Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes
J. Clin. Invest. Raymond J. Steptoe, et al. 111:1357 doi:10.1172/JCI15995 [
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Figure 4Reconstitution of PBL in recipients of T cell–depleted NOD or NOD-PI BM. PBLs were markedly depleted at 10–14 days but reconstituted by 8 weeks after irradiation and BMT in both NOD (inverted triangles) and NOD-PI (triangles) T cell–depleted BM recipients as compared with untreated age-matched NOD mice (squares).