Differential subunit composition of the G protein–activated inward-rectifier potassium channel during cardiac development
J. Clin. Invest. Bernd K. Fleischmann, et al. 114:994 doi:10.1172/JCI15925 [Go to this article.]

Figure 4
Time course of CCh-induced I_K,ACh differs between early- and late-stage cardiomyocytes. (A and B) Upper panel: I_K,ACh recorded in response to a voltage step from 0 to _100 mV under symmetrical K⁺ conditions in an early- and late-stage cardiomyocyte derived from atria (A) or ES cells (B, recorded with perforated patch). Lower panel: relative contribution of the instantaneous component (I₀) to maximal I_K,ACh amplitude (I_max) as measured in individual early- and late-stage cardiomyocytes derived from atria (A) or ES cells (B).