In this video collection, authors of findings published in The Journal of Clinical Investigation present personally guided tours of their results. The journal accepts video submissions from authors of recently accepted manuscripts. Instructions can be found on the Author's Take Guidelines page.
In this episode, Raphaela Goldbach-Mansky, Adriana de Jesus, and colleagues use a comprehensive approach to identify autoinflammatory diseases that present with elevated interferon signature.
In this episode, Lars French, Takashi K. Satoh and colleagues show that EGFR/MEK inhibitors and the commensal Cutibacterium acnes synergistically induce IL-36γ in keratinocytes, resulting in neutrophilic acneiform skin toxicities.
In this episode, Alice Long and colleagues demonstrate a link between disease outcome in type 1 diabetes and the phenotype and function of autoreactive CD8+ T cells.
In this episode, Anil Chauhan, Manish Jain, and colleagues reveal that smooth muscle cell- specific fibronectin containing an extra domain A mediates phenotypic switching and neointimal hyperplasia.
In this episode, Nicolai van Oers and colleagues demonstrate that compound heterozygous mutations in FOXN1 result in a combined immunodeficiency in patients that is distinct Nude/SCID phenotypes.