It is nearly 20 years that nitric oxide (NO) entered the scene to become an integral
component in understanding physiological and pathophysiological processes ranging from
fine-tuned signaling to promoting cell demise. Among multiple activities attributed to NO we
find regulation of gene expression. Although there is no evidence for direct NO-responsive
DNA elements within promotor regions of eukaryotic genes numerous signaling pathways
exist to understand NO-regulated gene expression. A characteristic feature of may …