Biologics in eosinophilic gastrointestinal diseases

ES Dellon, JM Spergel - Annals of Allergy, Asthma & Immunology, 2023 - Elsevier
Eosinophilic gastrointestinal diseases are a constellation of conditions categorized by the
location of eosinophilic infiltration in the gastrointestinal tract. Symptoms vary based on
location of eosinophils and age of the patient. There are no approved medications at the
current time with individuals using off-label steroids or dietary therapy. Translational
research has identified potential pathways to target in the treatment of eosinophilic
esophagitis (EoE), gastritis (EoG), and enteritis (EoN), including type 2 pathways, mast cells …