Serum interleukin‐9 levels are associated with clinical severity in children with atopic dermatitis
G Ciprandi, M De Amici, V Giunta… - Pediatric …, 2013 - Wiley Online Library
G Ciprandi, M De Amici, V Giunta, A Marseglia, G Marseglia
Pediatric dermatology, 2013•Wiley Online LibraryAtopic dermatitis (AD) is an inflammatory disorder of the skin characterized by impaired
immune response. Th9 cells are a sub‐population of T cells that release interleukin (IL)‐9.
No study has investigated the role of IL‐9 in AD. This study compared 64 children with AD
with 45 healthy children. Serum IL‐9 levels were measured and clinical symptoms were
assessed. Children with AD had higher serum IL‐9 levels than controls (p= 0.01). Clinical
severity was significantly related to IL‐9 level, indicating that IL‐9 might exert a pathogenic …
immune response. Th9 cells are a sub‐population of T cells that release interleukin (IL)‐9.
No study has investigated the role of IL‐9 in AD. This study compared 64 children with AD
with 45 healthy children. Serum IL‐9 levels were measured and clinical symptoms were
assessed. Children with AD had higher serum IL‐9 levels than controls (p= 0.01). Clinical
severity was significantly related to IL‐9 level, indicating that IL‐9 might exert a pathogenic …
Abstract
Atopic dermatitis (AD) is an inflammatory disorder of the skin characterized by impaired immune response. Th9 cells are a sub‐population of T cells that release interleukin (IL)‐9. No study has investigated the role of IL‐9 in AD. This study compared 64 children with AD with 45 healthy children. Serum IL‐9 levels were measured and clinical symptoms were assessed. Children with AD had higher serum IL‐9 levels than controls (p = 0.01). Clinical severity was significantly related to IL‐9 level, indicating that IL‐9 might exert a pathogenic role in symptom occurrence in individuals with AD. Children with AD may have higher serum IL‐9 levels than healthy children, and IL‐9 levels are significantly related to symptom severity.
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