Increased Moraxella and Streptococcus species abundance after severe bronchiolitis is associated with recurrent wheezing

JM Mansbach, PN Luna, CA Shaw, K Hasegawa… - Journal of Allergy and …, 2020 - Elsevier
Background The role of the airway microbiome in the development of recurrent wheezing
and asthma remains uncertain, particularly in the high-risk group of infants hospitalized for
bronchiolitis. Objective We sought to examine the relation of the nasal microbiota at
bronchiolitis-related hospitalization and 3 later points to the risk of recurrent wheezing by
age 3 years. Methods In 17 US centers researchers collected clinical data and nasal swabs
from infants hospitalized for bronchiolitis. Trained parents collected nasal swabs 3 weeks …