Circulating CD8+ CD56− perforin+ T cells are increased in multiple sclerosis patients

G Frisullo, D Plantone, A Marti, R Iorio, V Nociti… - Journal of …, 2011 - Elsevier
Relapsing–remitting multiple sclerosis (RRMS), secondary progressive (SP) MS and primary
progressive (PP) MS patients showed higher percentages of circulating CD8+ CD56−
perforin+ T cells than controls whereas only relapsing RRMS and PPMS patients showed
higher perforin expression in CD8+ CD56− T cells than controls. MS patients with EDSS≥ 3
showed higher percentage of CD8+ CD56− perforin+ T cells than patients with EDSS< 3
and controls whereas patients with EDSS< 3 showed higher percentage of this T cell …