BMP4 mediates myocardial inflammation and fibrosis
P Martín - Nature Cardiovascular Research, 2024 - nature.com
Nature Cardiovascular Research, 2024•nature.com
Myocarditis, an inflammatory heart disease, causes cardiomyocyte loss leading to heart
failure. Research now shows that BMP4 is crucial for cardiac tissue homeostasis, and
targeted neutralization of BMP inhibitors GREM1 and GREM2 mitigates T cell-induced
myocardial inflammation and maintains cardiomyocyte integrity.
failure. Research now shows that BMP4 is crucial for cardiac tissue homeostasis, and
targeted neutralization of BMP inhibitors GREM1 and GREM2 mitigates T cell-induced
myocardial inflammation and maintains cardiomyocyte integrity.
Myocarditis, an inflammatory heart disease, causes cardiomyocyte loss leading to heart failure. Research now shows that BMP4 is crucial for cardiac tissue homeostasis, and targeted neutralization of BMP inhibitors GREM1 and GREM2 mitigates T cell-induced myocardial inflammation and maintains cardiomyocyte integrity.
nature.com