Genetic and environmental influences on alcohol, caffeine, cannabis, and nicotine use from early adolescence to middle adulthood

KS Kendler, E Schmitt, SH Aggen… - Archives of general …, 2008 - jamanetwork.com
Context While both environmental and genetic factors are important in the etiology of
psychoactive substance use (PSU), we know little of how these influences differ through
development. Objective To clarify the changing role of genes and environment in PSU from
early adolescence through middle adulthood. Design Retrospective assessment by life
history calendar, with univariate and bivariate structural modeling. Setting General
community. Participants A total of 1796 members of male-male pairs from the Virginia Adult …