In vivo imaging of translocator protein in long-term cannabis users

T Da Silva, S Hafizi, JJ Watts, CS Weickert… - Jama …, 2019 - jamanetwork.com
Importance Cannabis is the most commonly used illicit drug in the world. Cannabinoids
have been shown to modulate immune responses; however, the association of cannabis
with neuroimmune function has never been investigated in vivo in the human brain.
Objective To investigate neuroimmune activation or 18-kDa translocator protein (TSPO)
levels in long-term cannabis users, and to evaluate the association of brain TSPO levels with
behavioral measures and inflammatory blood biomarkers. Design, Setting, and Participants …