Wnt signaling and injury repair
JL Whyte, AA Smith, JA Helms - Cold Spring Harbor …, 2012 - cshperspectives.cshlp.org
JL Whyte, AA Smith, JA Helms
Cold Spring Harbor perspectives in biology, 2012•cshperspectives.cshlp.orgWnt signaling is activated by wounding and participates in every subsequent stage of the
healing process from the control of inflammation and programmed cell death, to the
mobilization of stem cell reservoirs within the wound site. In this review we summarize recent
data elucidating the roles that the Wnt pathway plays in the injury repair process. These data
provide a foundation for potential Wnt-based therapeutic strategies aimed at stimulating
tissue regeneration.
healing process from the control of inflammation and programmed cell death, to the
mobilization of stem cell reservoirs within the wound site. In this review we summarize recent
data elucidating the roles that the Wnt pathway plays in the injury repair process. These data
provide a foundation for potential Wnt-based therapeutic strategies aimed at stimulating
tissue regeneration.
Wnt signaling is activated by wounding and participates in every subsequent stage of the healing process from the control of inflammation and programmed cell death, to the mobilization of stem cell reservoirs within the wound site. In this review we summarize recent data elucidating the roles that the Wnt pathway plays in the injury repair process. These data provide a foundation for potential Wnt-based therapeutic strategies aimed at stimulating tissue regeneration.
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