Alcohol use disorder (AUD) is a widespread disease with limited treatment options.
Targeting the neuroimmune system is a new avenue for developing or repurposing effective
pharmacotherapies. Alcohol modulates innate immune signaling in different cell types in the
brain by altering gene expression and the molecular pathways that regulate
neuroinflammation. Chronic alcohol abuse may cause an imbalance in neuroimmune
function, resulting in prolonged perturbations in brain function. Likewise, manipulating the …