Rules for making human tumor cells
WC Hahn, RA Weinberg - New England Journal of Medicine, 2002 - Mass Medical Soc
WC Hahn, RA Weinberg
New England Journal of Medicine, 2002•Mass Medical SocThe apparent complexity of the genetic, biochemical, and physiological changes in cancer
cells threatens to stall the elucidation of the origins of cancer and the development of new
treatments for malignant diseases. The authors propose a considerably simplified scheme in
which only five alterations are required to transform cells from a normal to a malignant
phenotype.
cells threatens to stall the elucidation of the origins of cancer and the development of new
treatments for malignant diseases. The authors propose a considerably simplified scheme in
which only five alterations are required to transform cells from a normal to a malignant
phenotype.
The apparent complexity of the genetic, biochemical, and physiological changes in cancer cells threatens to stall the elucidation of the origins of cancer and the development of new treatments for malignant diseases. The authors propose a considerably simplified scheme in which only five alterations are required to transform cells from a normal to a malignant phenotype.
The New England Journal Of Medicine