Signaling mechanisms for regulation of chemotaxis

D Wu - Cell research, 2005 - nature.com
D Wu
Cell research, 2005nature.com
Chemotaxis is a fascinating biological process, through which a cell migrates along a
shallow chemoattractant gradient that is less than 5% difference between the anterior and
posterior of the cell. Chemotaxis is composed of two independent, but interrelated processes-
motility and directionality, both of which are regulated by extracellular stimuli,
chemoattractants. In this mini-review, recent progresses in the understanding of the
regulation of leukocyte chemotaxis by chemoattractant signaling are reviewed.
Abstract
Chemotaxis is a fascinating biological process, through which a cell migrates along a shallow chemoattractant gradient that is less than 5% difference between the anterior and posterior of the cell. Chemotaxis is composed of two independent, but interrelated processes-motility and directionality, both of which are regulated by extracellular stimuli, chemoattractants. In this mini-review, recent progresses in the understanding of the regulation of leukocyte chemotaxis by chemoattractant signaling are reviewed.
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