Hyperlipidemia is an important risk factor for cardiovascular disease globally, but there is still
much mystery surrounding the topic of lipid regulation. Many studies have attempted to
assess the underlying genetic basis of low-density lipoprotein (LDL) metabolism. Recently,
multiple genome-wide association studies identified genes that strongly associate with
plasma lipid concentration and cardiovascular disease. Compelling evidence linking the
SORT1 gene to both LDL cholesterol (LDL-C) levels and the risk of coronary artery disease …