[PDF][PDF] Cellular functions of proteoglycans—an overview

N Perrimon, M Bernfield - Seminars in cell & developmental …, 2001 - projects.iq.harvard.edu
This issue of Seminars in Cell and Developmental Biology contains a number of articles
reviewing the cellular functions of proteoglycans. Proteoglycans are proteins, substituted
with glycosaminoglycans (GAGs), that generally either decorate the cell membrane or fill the
extracellular space. GAGs are linear polysaccharides consisting of a repeating disaccharide,
generally of an acetylated amino sugar alternating with a uronic acid. Although there are
intracellular types, most proteoglycans are destined for the extracellular space. These are …