Foxa2: the rise and fall of dopamine neurons
E Arenas - Cell stem cell, 2008 - cell.com
Cell stem cell, 2008•cell.com
Understanding the development and maintenance of dopamine neurons is essential to
establish novel stem cell therapies and animal models of Parkinson's disease. A recent
PLoS Biology report (Kittappa et al., 2007) reveals that Foxa2 regulates dopamine neuron
generation and differentiation, and that aging foxa2+/− mice spontaneously develop
Parkinsonism.
establish novel stem cell therapies and animal models of Parkinson's disease. A recent
PLoS Biology report (Kittappa et al., 2007) reveals that Foxa2 regulates dopamine neuron
generation and differentiation, and that aging foxa2+/− mice spontaneously develop
Parkinsonism.
Understanding the development and maintenance of dopamine neurons is essential to establish novel stem cell therapies and animal models of Parkinson's disease. A recent PLoS Biology report (Kittappa et al., 2007) reveals that Foxa2 regulates dopamine neuron generation and differentiation, and that aging foxa2+/− mice spontaneously develop Parkinsonism.
cell.com
