Type 1 diabetes mellitus (T1DM) is a chronic disease resulting from autoimmune destruction of insulin secreting beta cells of the pancreas. Worldwide the number of new T1DM cases is on a continuous rise despite extensive research efforts during the past decades. Patients with T1DM require lifelong insulin replacement. Currently T1DM patients are put on a high carbohydrate/low fat diet, a practice which has recently been criticized by several investigators. Here we report our second case of T1DM successfully treated with the paleolithic ketogenic diet, an animal meat-fat based diet, which is the opposite of the standard diabetes diet in several respects. The 9-year-old child initially followed the traditional diabetes diet with insulin replacement. After six weeks the child switched to the paleolithic ketogenic diet under our close control. He was able to discontinuate insulin while maintaining normoglycemia. Stimulated C peptide level was in the normal range at 14 months after diet onset. Currently he is on the diet and is without insulin for 19 months which is well beyond the “honeymoon” period. While on the paleolithic ketogenic diet subsequent laboratory work ups were normal and no side effects emerged. Following the dietary shift his eczema disappeared, the number of upper respiratory infections greatly reduced and improved physical fittness was noted. We assume that in new-onset cases of T1DM adopting the paleolithic ketogenic diet may be feasible and effective in managing this condition. It seems that the autoimmune process may halt when strictly adhering to the diet.