[HTML][HTML] Scavenger receptor class B, type I, mediates selective uptake of low density lipoprotein cholesteryl ester

S Swarnakar, RE Temel, MA Connelly, S Azhar… - Journal of Biological …, 1999 - ASBMB
Scavenger receptor, class B, type I (SR-BI) is a cell-surface glycoprotein that mediates
selective uptake of high density lipoprotein cholesteryl ester (CE) without the concomitant
uptake and degradation of the particle. We have investigated the endocytic and selective
uptake of low density lipoprotein (LDL)-CE by SR-BI using COS-7 cells transiently
transfected with mouse SR-BI. Analysis of lipoprotein uptake data showed a concentration-
dependent LDL-CE-selective uptake when doubly labeled LDL particles were incubated …