[HTML][HTML] In vivo regulation of scavenger receptor BI and the selective uptake of high density lipoprotein cholesteryl esters in rat liver parenchymal and Kupffer cells
K Fluiter, DR van der Westhuijzen… - Journal of Biological …, 1998 - ASBMB
High density lipoprotein cholesteryl esters (HDL-CE) are selectively taken up by liver
parenchymal cells without parallel apolipoprotein uptake. This selective uptake route forms
an important step in the so-called reverse cholesterol transport. Scavenger receptor BI (SR-
BI) is the only known HDL receptor which can mediate selective uptake of HDL-CE. In the
present study we investigated its regulation in liver cells. The down-regulation of SR-BI
expression in liver by 17α-ethinyl estradiol (EE) treatment was found by immunoblotting to …
parenchymal cells without parallel apolipoprotein uptake. This selective uptake route forms
an important step in the so-called reverse cholesterol transport. Scavenger receptor BI (SR-
BI) is the only known HDL receptor which can mediate selective uptake of HDL-CE. In the
present study we investigated its regulation in liver cells. The down-regulation of SR-BI
expression in liver by 17α-ethinyl estradiol (EE) treatment was found by immunoblotting to …
