Firing up glycolysis: BCG vaccination effects on type 1 diabetes mellitus
R Stienstra, MG Netea - Trends in Endocrinology & Metabolism, 2018 - Elsevier
R Stienstra, MG Netea
Trends in Endocrinology & Metabolism, 2018•ElsevierIn addition to the impact of Bacillus Calmette–Guerin (BCG) vaccination on antimicrobial
host defence, a novel study reveals beneficial effects on glycaemic control in patients with
long-standing type 1 diabetes mellitus (T1DM). These effects are ascribed to an accelerated
glucose consumption in immune cells due to increased glycolysis and reduced oxidative
phosphorylation.
host defence, a novel study reveals beneficial effects on glycaemic control in patients with
long-standing type 1 diabetes mellitus (T1DM). These effects are ascribed to an accelerated
glucose consumption in immune cells due to increased glycolysis and reduced oxidative
phosphorylation.
In addition to the impact of Bacillus Calmette–Guerin (BCG) vaccination on antimicrobial host defence, a novel study reveals beneficial effects on glycaemic control in patients with long-standing type 1 diabetes mellitus (T1DM). These effects are ascribed to an accelerated glucose consumption in immune cells due to increased glycolysis and reduced oxidative phosphorylation.
Elsevier