Dynamic mechanical analysis to assess viscoelasticity of liver tissue in a rat model of nonalcoholic fatty liver disease

X Zhang, X Gao, P Zhang, Y Guo, H Lin, X Diao… - Medical Engineering & …, 2017 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disorder in both
developed and developing countries. A noninvasive method of detecting early stage NAFLD
and distinguishing non-alcoholic steatohepatitis (NASH) from simple steatosis (SS) would
be useful. The over-accumulation of fat in hepatocytes alters the physical microstructure and
chemical contents of the liver tissue. This study included dynamic mechanical analysis
(DMA) testing on liver samples from a rat model of NAFLD to determine whether the tissue …