Background Food allergy is a growing health problem with very limited treatment options.
Investigation of the immunologic pathways underlying allergic sensitization to foods in
humans has been greatly constrained by the limited availability of intestinal tissue and gut-
resident immune cells. Although mouse models have offered insights into pathways of food
sensitization, differences between rodent and human immune physiology limit the extension
of these findings to our understanding of human disease. Objective We sought to develop a …