Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins
BL Black, EN Olson - Annual review of cell and developmental …, 1998 - annualreviews.org
▪ Abstract Metazoans contain multiple types of muscle cells that share several common
properties, including contractility, excitability, and expression of overlapping sets of muscle
structural genes that mediate these functions. Recent biochemical and genetic studies have
demonstrated that members of the myocyte enhancer factor-2 (MEF2) family of MADS
(MCM1, agamous, deficiens, serum response factor)-box transcription factors play multiple
roles in muscle cells to control myogenesis and morphogenesis. Like other MADS-box …
properties, including contractility, excitability, and expression of overlapping sets of muscle
structural genes that mediate these functions. Recent biochemical and genetic studies have
demonstrated that members of the myocyte enhancer factor-2 (MEF2) family of MADS
(MCM1, agamous, deficiens, serum response factor)-box transcription factors play multiple
roles in muscle cells to control myogenesis and morphogenesis. Like other MADS-box …