Structures of Toxoplasma gondiiTachyzoites, Bradyzoites, and Sporozoites and Biology and Development of Tissue Cysts

JP Dubey, DS Lindsay, CA Speer - Clinical microbiology reviews, 1998 - journals.asm.org
JP Dubey, DS Lindsay, CA Speer
Clinical microbiology reviews, 1998journals.asm.org
Infections by the protozoan parasite Toxoplasma gondii are widely prevalent worldwide in
animals and humans. This paper reviews the life cycle; the structure of tachyzoites,
bradyzoites, oocysts, sporocysts, sporozoites and enteroepithelial stages of T. gondii; and
the mode of penetration of T. gondii. The review provides a detailed account of the biology of
tissue cysts and bradyzoites including in vivo and in vitro development, methods of
separation from host tissue, tissue cyst rupture, and relapse. The mechanism of in vivo and …
Summary
Infections by the protozoan parasite Toxoplasma gondii are widely prevalent worldwide in animals and humans. This paper reviews the life cycle; the structure of tachyzoites, bradyzoites, oocysts, sporocysts, sporozoites and enteroepithelial stages of T. gondii; and the mode of penetration of T. gondii. The review provides a detailed account of the biology of tissue cysts and bradyzoites including in vivo and in vitro development, methods of separation from host tissue, tissue cyst rupture, and relapse. The mechanism of in vivo and in vitro stage conversion from sporozoites to tachyzoites to bradyzoites and from bradyzoites to tachyzoites to bradyzoites is also discussed.
American Society for Microbiology