[HTML][HTML] Structure of the chromo barrel domain from the MOF acetyltransferase
PR Nielsen, D Nietlispach, A Buscaino… - Journal of Biological …, 2005 - ASBMB
We report here the structure of the putative chromo domain from MOF, a member of the
MYST family of histone acetyltransferases that acetylates histone H4 at Lys-16 and is part of
the dosage compensation complex in Drosophila. We found that the structure of this domain
is a β-barrel that is distinct from the α+ β fold of the canonical chromo domain. Despite the
differences, there are similarities that support an evolutionary relationship between the two
domains, and we propose the name" chromo barrel." The chromo barrel domains may be …
MYST family of histone acetyltransferases that acetylates histone H4 at Lys-16 and is part of
the dosage compensation complex in Drosophila. We found that the structure of this domain
is a β-barrel that is distinct from the α+ β fold of the canonical chromo domain. Despite the
differences, there are similarities that support an evolutionary relationship between the two
domains, and we propose the name" chromo barrel." The chromo barrel domains may be …