[HTML][HTML] Deficiency of the chromatin regulator BRPF1 causes abnormal brain development
Epigenetic mechanisms are important in different neurological disorders, and one such
mechanism is histone acetylation. The multivalent chromatin regulator BRPF1
(bromodomain-and plant homeodomain-linked (PHD) zinc finger-containing protein 1)
recognizes different epigenetic marks and activates three histone acetyltransferases, so it is
both a reader and a co-writer of the epigenetic language. The three histone
acetyltransferases are MOZ, MORF, and HBO1, which are also known as lysine …
mechanism is histone acetylation. The multivalent chromatin regulator BRPF1
(bromodomain-and plant homeodomain-linked (PHD) zinc finger-containing protein 1)
recognizes different epigenetic marks and activates three histone acetyltransferases, so it is
both a reader and a co-writer of the epigenetic language. The three histone
acetyltransferases are MOZ, MORF, and HBO1, which are also known as lysine …