[HTML][HTML] Deficiency of the chromatin regulator BRPF1 causes abnormal brain development

L You, J Zou, H Zhao, NR Bertos, M Park… - Journal of Biological …, 2015 - ASBMB
Epigenetic mechanisms are important in different neurological disorders, and one such
mechanism is histone acetylation. The multivalent chromatin regulator BRPF1
(bromodomain-and plant homeodomain-linked (PHD) zinc finger-containing protein 1)
recognizes different epigenetic marks and activates three histone acetyltransferases, so it is
both a reader and a co-writer of the epigenetic language. The three histone
acetyltransferases are MOZ, MORF, and HBO1, which are also known as lysine …