Laronidase hypersensitivity and desensitization in type I mucopolysaccharidosis: a case report.
LF Ensina, CS Aranda, AE Lacerda… - Pediatric Allergy & …, 2014 - search.ebscohost.com
Pediatric Allergy & Immunology, 2014•search.ebscohost.com
Laronidase hypersensitivity and desensitization in type I mucopolysaccharidosis: a case report
Page 1 CORRESPONDENCE Laronidase hypersensitivity and desensitization in type I
mucopolysaccharidosis: a case report To the Editor, Mucopolysaccharidosis-I (MPS-I) is a
lysosomal storage disorder, resulting from the deficiency of lysosomal alpha-Liduronidase
enzyme. It is a rare disorder, with an estimated prevalence ranging from 0.69 to 3.8 per 100,000
live births (1). The disorder affects independently the central nervous, skeletal, digestive …
Page 1 CORRESPONDENCE Laronidase hypersensitivity and desensitization in type I
mucopolysaccharidosis: a case report To the Editor, Mucopolysaccharidosis-I (MPS-I) is a
lysosomal storage disorder, resulting from the deficiency of lysosomal alpha-Liduronidase
enzyme. It is a rare disorder, with an estimated prevalence ranging from 0.69 to 3.8 per 100,000
live births (1). The disorder affects independently the central nervous, skeletal, digestive …
Abstract
A letter to the editor is presented regarding the case of an 11-year-old female referred to an outpatient clinic for evaluation of hypersensitivity reactions during enzyme replacement therapy (ERT) with laronidase.
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