Purification of neuronal precursors from the adult mouse brain: comprehensive gene expression analysis provides new insights into the control of cell migration …

S Pennartz, R Belvindrah, S Tomiuk, C Zimmer… - Molecular and Cellular …, 2004 - Elsevier
The progeny of neural stem cells in the subventricular zone (SVZ) of the adult mammalian
brain consists in polysialylated NCAM-expressing immature neurons (PSA+ cells), which
migrate to the olfactory bulb (OB) to differentiate into GABAergic interneurons. We purified
murine PSA+ cells directly from the adult brain by FACS and analyzed their gene expression
profile by SAGE. Comparative analyses led to the identification of precursor-enriched genes,
including Survivin, Sox-4, Meis2, Dishevelled-2, C3aR1 and Riken 3110003A17, and many …