Long-term brain and behavioral consequences of early iron deficiency
MK Georgieff - Nutrition reviews, 2011 - academic.oup.com
MK Georgieff
Nutrition reviews, 2011•academic.oup.comEarly iron deficiency not only affects brain and behavioral function during the period of iron
deficiency, it persists long after treatment. The mechanisms include long-term alterations in
dopamine metabolism, myelination, and hippocampal structure and function. Recent studies
have demonstrated long-term genomic changes, which suggests the regulation of brain
function is fundamentally altered.
deficiency, it persists long after treatment. The mechanisms include long-term alterations in
dopamine metabolism, myelination, and hippocampal structure and function. Recent studies
have demonstrated long-term genomic changes, which suggests the regulation of brain
function is fundamentally altered.
Abstract
Early iron deficiency not only affects brain and behavioral function during the period of iron deficiency, it persists long after treatment. The mechanisms include long-term alterations in dopamine metabolism, myelination, and hippocampal structure and function. Recent studies have demonstrated long-term genomic changes, which suggests the regulation of brain function is fundamentally altered.
Oxford University Press