Association of prenatal exposure to air pollution with autism spectrum disorder

L Pagalan, C Bickford, W Weikum, B Lanphear… - JAMA …, 2019 - jamanetwork.com
Importance The etiology of autism spectrum disorder (ASD) is poorly understood, but prior
studies suggest associations with airborne pollutants. Objective To evaluate the association
between prenatal exposures to airborne pollutants and ASD in a large population-based
cohort. Design, Setting, and Participants This population-based cohort encompassed nearly
all births in Metro Vancouver, British Columbia, Canada, from 2004 through 2009, with
follow-up through 2014. Children were diagnosed with ASD using a standardized …