Muscle slowness in a family with nemaline myopathy

IMP Pauw-Gommans, KHL Gerrits, A de Haan… - Neuromuscular …, 2006 - Elsevier
All patients of a large family with nemaline myopathy complained of slowness in movement.
We confirmed this clinical complaint physiologically by showing lower contractile speed in
quadriceps muscle. Electrically evoked contractions of the quadriceps muscle elicited a
lower rate of relaxation and a tendency for slower torque generation. Here, we demonstrate
for the first time slow muscle characteristics as a physiological correlate for the clinical
complaint of slowness.