Albuminuria and kidney function independently predict cardiovascular and renal outcomes in diabetes

T Ninomiya, V Perkovic, BE De Galan… - Journal of the …, 2009 - journals.lww.com
There are limited data regarding whether albuminuria and reduced estimated GFR (eGFR)
are separate and independent risk factors for cardiovascular and renal events among
individuals with type 2 diabetes. The Action in Diabetes and Vascular disease: preterAx and
diamicroN-MR Controlled Evaluation (ADVANCE) study examined the effects of routine BP
lowering on adverse outcomes in type 2 diabetes. We investigated the effects of urinary
albumin-to-creatinine ratio (UACR) and eGFR on the risk for cardiovascular and renal …