[HTML][HTML] Venous thrombosis and cancer: from mouse models to clinical trials

Y Hisada, JE Geddings, C Ay, N Mackman - Journal of Thrombosis and …, 2015 - Elsevier
Cancer patients have a~ 4 fold increased risk of venous thromboembolism (VTE) compared
with the general population and this is associated with significant morbidity and mortality.
This review summarizes our current knowledge of VTE and cancer, from mouse models to
clinical studies. Notably, the risk of VTE varies depending on the type and stage of cancer.
For instance, pancreatic and brain cancer patients have a higher risk of VTE than breast and
prostate cancer patients. Moreover, patients with metastatic disease have a higher risk than …