[HTML][HTML] Associations of RASSF1A, RARβ, and CDH1 promoter hypermethylation with oral cancer risk: A PRISMA-compliant meta-analysis
G Wen, H Wang, Z Zhong - Medicine, 2018 - journals.lww.com
Background: Oral tumor is a heterogeneous group of tumors, in which it has several different
histopathological and molecular features. Recently, genetic and epigenetic alterations are
often detected in the development of oral cancer. Gene promoter hypermethylation leads to
the silencing of cancer related genes without changes of genes sequence. To clarify the
effect of RAS association domain family protein 1a (RASSF1A), retinoic acid receptor beta
(RARβ), and E-cadherin (CDH1) promoter hypermethylation on the risk of oral cancer, we …
histopathological and molecular features. Recently, genetic and epigenetic alterations are
often detected in the development of oral cancer. Gene promoter hypermethylation leads to
the silencing of cancer related genes without changes of genes sequence. To clarify the
effect of RAS association domain family protein 1a (RASSF1A), retinoic acid receptor beta
(RARβ), and E-cadherin (CDH1) promoter hypermethylation on the risk of oral cancer, we …