Hyperoxia causes reduced density of retinal astrocytes in the central avascular zone in the mouse model of oxygen-induced retinopathy
F Bucher, A Stahl, HT Agostini, G Martin - Molecular and Cellular …, 2013 - Elsevier
The mouse model of oxygen-induced retinopathy (OIR) is commonly used to investigate
various aspects of the pathogenesis of the retinopathy of prematurity (ROP) as well as
angiogenesis in general. Retinal astrocytes were suggested to be involved in retinal
angiogenesis. This study aimed to describe their localization and cell density during the
course of physiological vascularization and pathological revascularization. Mice expressing
H2B-GFP (green fluorescent protein fused to histone 2B) from the endogenous Pdgfra …
various aspects of the pathogenesis of the retinopathy of prematurity (ROP) as well as
angiogenesis in general. Retinal astrocytes were suggested to be involved in retinal
angiogenesis. This study aimed to describe their localization and cell density during the
course of physiological vascularization and pathological revascularization. Mice expressing
H2B-GFP (green fluorescent protein fused to histone 2B) from the endogenous Pdgfra …